Prazitel Xl 20 Tablets

PHARMACOTHERAPEUTIC CATEGORY:  Antitrematodes, antinematodes, anticestodes. Praziquantel in combination.

COMPOSITION:

Active ingredients:  Praziquantel 175 mg, Pyrantel embonate 504 mg (equivalent to 175 mg of pyrantel), Febantel 525 mg.

Excipients:  Lactose monohydrate, Microcrystalline cellulose, Magnesium stearate, Colloidal anhydrous silica, Croscarmellose sodium, Sodium lauryl sulphate, Pork flavour.

INDICATIONS:

Adult dogs: treatment of mixed infections caused by nematodes and tapeworms of the following species. NEMATODES. Roundworms: Toxocara canis and Toxascaris leonina (adult and immature forms). Hookworms: Uncinaria stenocephala and Ancylostoma caninum (adults). Whipworms: Trichuris vulpis (adults). TAPEWORM. Tapeworms: Echinococcus spp , (E. granulosus, E. multilocularis), Taenia spp (T. hydatigena, T. pisiformis, T. taeniformis) and Dipylidium caninum (adult and immature forms).

CONTRAINDICATIONS/SIDE EFFECTS:

Do not use in cases of hypersensitivity to the active ingredients or to any of the excipients.

PHARMACEUTICAL FORM: Tablets

USE/ROUTE OF ADMINISTRATION:

For oral use.

POSOLOGY:

Administer orally only. For dosages, follow the indications below: 15 mg/kg of body weight for febantel, 5 mg/kg for pyrantel (equivalent to 14.4 mg pyrantel embonate) and 5 mg/kg for praziquantel equivalent to 1 tablet for 35 kg. of body weight. Dogs weighing more than 35 kg should be given 1 Prazitel tablet for large dogs, plus the correct dose of Prazitel tablets for dogs equivalent to 1 tablet for every 10 kg. Dogs weighing 17.5 kg should be given 1 Prazitel tablet for large dogs, plus the correct dose of Prazitel tablets for dogs equivalent to 1 tablet for every 10 kg. kg should be administered 1/2 tablet of Prazitel tablets for large dogs. The tablets can be administered directly to the dog or hidden in food. A fasting period is not necessary, neither before nor after treatment. If there is a risk of reinfestation, consult a veterinarian to request guidance on the need and frequency of further administrations.

STORAGE:

This veterinary medicinal product does not require any special storage conditions. The half tablets should be placed in the appropriate space in the blister and this stored in the cardboard box.

WARNINGS:

Fleas are the intermediate hosts for a common type of tapeworm, Dipylidium caninum. Tapeworm infestation will certainly recur if no control measures are taken on intermediate hosts, such as fleas, mice, etc. Resistance of a parasite to a particular class of anthelmintics may develop following frequent, repeated use of an anthelmintic of that class. To ensure correct dosing, body weight should be determined as accurately as possible. Special precautions to be taken by the person administering the veterinary medicinal product to animals: In case of accidental ingestion, seek medical advice immediately and show the package leaflet to the physician. In accordance with good hygiene practice, wash hands after administering the tablets directly to the dog or after adding them to its food. Overdose: The combined administration of praziquantel, pyrantel embonate and febantel is well tolerated by dogs. In safety studies, doses five or more times higher than those recommended have occasionally resulted in vomiting.

TARGET SPECIES:

Large breed dogs.

INTERACTIONS:

Do not administer piperazine compounds simultaneously since the anthelmintic effects of pyrantel and piperazine may be antagonized. Concomitant use of other cholinergic compounds may cause toxicity.

DIAGNOSIS AND PRESCRIPTION:

Veterinary medicine without a prescription.

PREGNANCY AND BREASTFEEDING:

Teratogenic effects attributed to high doses of febantel have been reported in sheep and mice. No studies have been performed in bitches during the first part of pregnancy. The use of the product during pregnancy must be subject to a risk/benefit assessment. It is recommended not to use the product in bitches during the first 4 weeks of pregnancy. Do not exceed the recommended dose when treating pregnant bitches.