Panadron Plus XL 2 Cane Compress

PHARMACOTHERAPEUTIC CATEGORY:  Anthelmintics

COMPOSITION:

Active ingredients:  Each tablet contains active ingredients: praziquantel 175 mg; pyrantel embonate 504 mg (equivalent to 175 mg of pyrantel); febantel 525 mg.

Excipients:  Microcrystalline cellulose, magnesium stearate, colloidal anhydrous silica, croscarmellose sodium, sodium lauryl sulphate, pork flavouring.

INDICATIONS:  Panadron is an anthelmintic for dogs that acts against intestinal worms, which can cause problems such as diarrhea, poor appetite, thinness. In dogs: treatment of mixed infections caused by roundworms and tapeworms of the following species: Roundworms: Ascarids: Toxocara canis and Toxascaris leonina (adult and immature forms). Hookworms: Uncinaria stenocephala and Ancylostoma caninum (adults). Whipworms: Trichuris vulpis (adults). Tapeworms: Tapeworms: Echinococcus spp, (E. granulosus, E. multilocularis), Taenia spp (T. hydatigena, T. pisiformis, T. taeniformis) and Dipylidium caninum (adult and immature forms).

CONTRAINDICATIONS/SIDE EFFECTS:  Do not administer simultaneously with piperazine compounds. Do not administer to animals with known hypersensitivity to the active substances or to any of the excipients. Do not administer during the first and second trimester of pregnancy

PHARMACEUTICAL FORM: Tablets

USE/ROUTE OF ADMINISTRATION: oral

DOSAGE: For oral administration only. To ensure administration of the correct dose, body weight should be determined as accurately as possible. Dosage: For the treatment of dogs, 1 tablet per 35 kg of body weight (15 mg febantel, 14.4 mg pyrantel embonate and 5 mg praziquantel/kg of body weight). The dosages are as follows. Body weight (kg): about 17.5kg; tablets: ½ panadron plus xl tablets for dogs. Body weight (kg): 31-35 kg; tablets: 1 panadron plus xl tablets for dogs. Body weight (kg): >35-40 kg; tablets: 1 panadron plus xl dog tablets + ½ panadron plus dog tablet. Body weight (kg): >40-45 kg; tablets: 1 panadron plus xl tablets for dogs + 1 panadron plus tablet for dogs. Body weight (kg): >45-50 kg; tablets: 1 panadron plus xl dog tablets + 1 ½ panadron plus dog tablet. Body weight (kg): >50-55 kg; tablets: 1 panadron plus xl tablets for dogs + 2 panadron plus tablets for dogs. Body weight (kg): >55-60 kg; tablets: 1 panadron plus xl tablet for dogs + 2 ½ panadron plus tablet for dogs. Body weight (kg): >60-65 kg; tablets: 1 panadron plus xl tablets for dogs + 3 panadron plus tablets for dogs. Body weight (kg): >65-70 kg; tablets: 2 panadron plus xl tablets for dogs. The tablets can be administered directly to the dog or hidden in food. A fasting period is not necessary, either before or after treatment. The tablets should be given in a single administration. Tablet parts should be discarded immediately or returned to the opened blister until used. If there is a risk of reinfestation, contact a veterinarian to request information on the need and frequency of other administrations.

STORAGE:  This veterinary medicinal product does not require any special storage conditions. Shelf life of the veterinary medicinal product packaged for sale: 5 years. Discard unused tablet fractions.

WARNINGS:  Fleas are the intermediate hosts of a common type of tapeworm, called Dipylidium caninum. Tapeworm infestation will certainly recur if control measures are not implemented on intermediate hosts, such as fleas, mice, etc. Tapeworm infestation is unlikely in puppies younger than 6 weeks. Resistance of a parasite to a particular class of anthelmintics may develop following frequent, repeated use of an anthelmintic of that class. Special precautions for use in animals: none. Special precautions to be taken by the person administering the veterinary medicinal product to animals: in case of accidental ingestion, contact a doctor immediately and show him the package leaflet. In compliance with hygiene rules, wash your hands after administering the tablets directly to the dog or after adding them to his food. In safety studies, doses five or more times higher than recommended occasionally caused vomiting. Incompatibility: not applicable.

TARGET SPECIES:  Dogs

WAITING TIME:  Not applicable. 

INTERACTIONS:  Do not administer simultaneously with piperazine compounds as the anthelmintic effects of pyrantel and piperazine may be antagonized.Concomitant use of other cholinergic compounds may cause toxicity.

DIAGNOSIS AND PRESCRIPTION: Veterinary medicine without the obligation of a veterinary prescription.

SIDE EFFECTS: In very rare cases, gastrointestinal disorders (diarrhea, emesis) have been observed. The frequency of adverse reactions is defined using the following conventions: very common (more than 1 in 10 treated animals experiences adverse reactions); common (more than 1 but less than 10 animals per 100 animals treated); uncommon (more than 1 but less than 10 animals per 1,000 animals treated); rare (more than 1 but less than 10 animals out of 10,000 animals treated); very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

PREGNANCY AND LACTATION: Teratogenic effects attributed to high doses of febantel have been reported in sheep and mice. No studies have been performed in bitches during the early part of pregnancy. The use of the product during pregnancy must be subject to an evaluation of the benefit/risk ratio by the responsible veterinarian. It is recommended not to use the product in bitches during the first 4 weeks of pregnancy. Do not exceed the recommended dose when treating pregnant dogs.