Bioforlife Therapet - Theratest Vaxintest - Cav/cdv/cpv Ab 5 test

CDV, CAV, and CPV-2 serology tests can determine protective immunity in puppies, establish revaccination intervals in adult dogs, and manage infectious disease outbreaks in kennels.

The Vaccination Guidelines Group (VGG) recognizes principles of “evidence-based veterinary medicine” which suggest that testing antibody status (in puppies and adults) is better practice than simply administering a booster vaccine on the basis that this it is “safe and cheaper”.

The objective of THERATEST VAXINTEST is to determine the level of antibodies to Canine Adenovirus (CAV types 1 and 2), Canine Distemper virus (CDV) and Canine Parvovirus (CPV type 2) in puppies and dogs adults. The titer of antibodies to these viruses is measured by an immunochromatographic rapid test for the semiquantitative detection of immunoglobulin G (IgG) in canine whole blood, serum or plasma. When the sample is absorbed by the test swab, the canine IgG antibodies bind to the antigens on the swab. Subsequently, the antibodies conjugated to the colloidal gold bind to the antigens creating an antibody-antibody-antigen (Ab-Ab-Ag) complex in the nitrocellulose membrane. Control Line (C): This line should appear regardless of the presence of CAV, CDV, or CPV antibodies. If the line does not appear, the test is to be considered void. Test Line (T): Indicates the presence of CAV, CDV, and CPV antibodies in whole blood, serum, or plasma of the dog. The antibody titre is determined by comparing the intensity of the C and T lines

A negative test result indicates that the dog has little or no antibodies, and therefore revaccination is recommended. Some seronegative dogs are de facto immune (false negative) and their revaccination would be useless as they would have a rapid and remarkable anamnestic response to vaccination (Mouzin et al. 2004). However, these dogs cannot be detected easily and an animal with a negative result, whichever test is used, should be considered antibody-free and therefore potentially susceptible to infection. Conversely, a positive test result should lead to the conclusion that revaccination is not required.