Panadron Plus 6 Cane Compress

PHARMACOTHERAPEUTIC CATEGORY:  Anthelmintics

COMPOSITION:

Active ingredients:  Each tablet contains: praziquantel: 50 mg; pyrantel: 50 mg (equivalent to 144 mg pyrantel embonate); febantel: 150 mg.

Excipients:  Lactose monohydrate; microcrystalline cellulose; magnesium stearate; anhydrous colloidal silica; croscarmellose sodium; sodium lauryl sulfate; pork flavour.

INDICATIONS:  Panadron is an anthelmintic for dogs that acts against intestinal worms, which can cause problems such as diarrhea, poor appetite, thinness. In dogs: treatment of mixed infections caused by roundworms and tapeworms of the following species: Roundworms: Ascarids: Toxocara canis and Toxascaris leonina (adult and immature forms). Hookworms: Uncinaria stenocephala and Ancylostoma caninum (adults). Whipworms: Trichuris vulpis (adults). Tapeworms: Tapeworms: Echinococcus spp, (E. granulosus, E. multilocularis), Taenia spp (T. hydatigena, T. pisiformis, T. taeniformis) and Dipylidium caninum (adult and immature forms).

CONTRAINDICATIONS/SIDE EFFECTS:  Do not administer simultaneously with piperazine compounds. Do not administer to animals with known hypersensitivity to the active substances or to any of the excipients. Do not administer the medicine during the first 4 weeks of pregnancy.

PHARMACEUTICAL FORM: Tablets

USE/ROUTE OF ADMINISTRATION: oral

POSOLOGY: For single oral administration. For dosages, follow the following indications: 15 mg/kg of body weight for febantel, 5 mg/kg for pyrantel (equivalent to 14.4 mg of pyrantel embonate) and 5 mg/kg for praziquantel. 1 tablet per 10 kg of body weight. The tablets can be administered directly to the dog or hidden in food. Neither before nor after treatment is a fasting period necessary. If there is a risk of re-infestation, contact a veterinarian to request information on the need and frequency of other administrations.

STORAGE: This veterinary medicinal product does not require any special storage conditions. Shelf life of the veterinary medicinal product packaged for sale: 5 years. Discard any unused tablet fractions.

WARNINGS: Fleas are the intermediate hosts of a common type of tapeworm, called Dipylidium caninum. Tapeworm infestation will certainly recur if control measures are not implemented on intermediate hosts, such as fleas, mice, etc. Tapeworm infestation is unlikely in puppies younger than 6 weeks. Resistance of a parasite to a particular class of anthelmintics may develop following frequent, repeated use of an anthelmintic of that class. Special precautions for use in animals: none. Special precautions to be taken by the person administering the veterinary medicinal product to animals:in case of accidental ingestion, contact a doctor immediately and show him the information leaflet. In compliance with hygiene rules, wash your hands after administering the tablets directly to the dog or after adding them to his food. In safety studies, doses five or more times higher than recommended occasionally caused vomiting. Incompatibility: not applicable.

TARGET SPECIES:  Dogs

WAITING TIME:  Not applicable. 

INTERACTIONS:  Do not administer simultaneously with piperazine compounds as the anthelmintic effects of pyrantel and piperazine may be antagonized. Concomitant use of other cholinergic compounds may cause toxicity.

DIAGNOSIS AND PRESCRIPTION:  Veterinary medicine without the obligation of a veterinary prescription.

SIDE EFFECTS:  In very rare cases, gastrointestinal disorders (diarrhea, emesis) have been observed. The frequency of adverse reactions is defined using the following conventions: very common (more than 1 in 10 treated animals experiences adverse reactions); common (more than 1 but less than 10 animals per 100 animals treated); uncommon (more than 1 but less than 10 animals per 1,000 animals treated); rare (more than 1 but less than 10 animals out of 10,000 animals treated); very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

PREGNANCY AND BREASTFEEDING:  Teratogenic effects attributed to high doses of febantel have been reported in sheep and mice. No studies have been performed in bitches during the early part of pregnancy. The use of the product during pregnancy must be subject to an evaluation of the benefit/risk ratio by the responsible veterinarian. It is recommended not to use the product in bitches during the first 4 weeks of pregnancy. Do not exceed the recommended dose when treating pregnant dogs.